منابع مشابه
Mitochondria and cardiac hypertrophy.
• Normally, myocardial metabolism is almost exclusively aerobic. The substantial quantities of adenosine triphosphate (ATP) required for muscle contraction and the much smaller amounts necessary for the maintenance of functions such as ion transport, rhythmicity, and conduction and the synthesis of membrane and protein constituents of the myocardium are supplied almost exclusively by mitochondr...
متن کاملMitochondria and left ventricular hypertrophy
Left ventricular hypertrophy (LVH) is one of the vicious organ damages of essential hypertension. It contributes a lot to high mortality of essential hypertension due to sudden cardiac death, ventricular arrhythmia and heart failure. Many factors involve in the pathogenesis of hypertension-induced LVH including inherited variants as well as environmental factors. For the genic influence, nucleu...
متن کاملREGRESSION OF LEFT VENTRICULAR HYPERTROPHY AFTER SUCCESSFUL RENAL TRANSPLANTATION AMONG UREMIC PATIENTS
Recognition of the natural history and responsible leading factors for regression of left ventricular hypertrophy after successful renal transplantation are very important. The aim of this study was to assess the regression of left ventricular hypertrophy after successful renal transplantation among uremic patients. In this study 27 uremic patients (18 males and 9 females) with an average a...
متن کاملRenal hypertrophy in experimental diabetes.
The effect of short-term diabetes, 5 days after the administration of streptozotocin, on renal growth and the activity of alternative pathways of glucose metabolism was studied in immature (21-day-old) rats and in adult rats. The kidney weight increased by 28% in the adult diabetic rats, but by only 10% in the immature diabetic rats, relative to their age-matched control groups. The flux of glu...
متن کاملTuberin in renal cell hypertrophy
Renal hypertrophy is an important prognostic indicator of progression of renal disease. Tubular cells, in particular those of the proximal tubule, are primary targets of hyperglycemia. Chronic exposure of renal cells to high glucose resulted in elevation of blood glucose and contributed to the tubulointerstitial. In diabetes, the renal tubule is subject to both direct and indirect insults. Rena...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 1990
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.v15822